Peritoneal Mesothelioma

Malignant peritoneal mesothelioma is a rare type of cancer that occurs in the thin cell walls which surround the abdominal cavity, known as the peritoneum. This thin membrane acts a lubricant within the abdominal cavity so that surrounding organs and internal body structures may contract and expand within their normal body function.

Other types of mesothelioma cancer include malignant pleural mesothelioma, occurring in the cell wall surrounding the lungs, and malignant pericardial mesothelioma, which occurs in the pericardial lining of the hearth. Peritoneal mesothelioma is the second rarest form of the disease and accounts for approximately 20% of all mesothelioma cases each year.

What Causes Peritoneal Mesothelioma?

Peritoneal mesothelioma is known only to be caused by exposure to asbestos, a microscopic natural fiber that was used heavily in industry. Asbestos is said to reach the abdominal wall by one of two methods. The first is through ingested asbestos fibers which are processed through digestion and become lodged in peritoneum. These other method is through the lungs and lymph nodes, by inhaled asbestos fibers. Malignant mesothelioma of the pleura is also known to metastasize directly into the abdominal cavity if its spread is not slowed.

Many of those who have worked with asbestos materials have developed peritoneal mesothelioma as a result of exposure to friable asbestos fibers. Asbestos was used in myriad industrial materials and construction products. Exposure to asbestos was common in aluminum plants, steel mills, power plants, and naval shipyards.

Peritoneal mesothelioma is a relatively rare disease, with only 200-500 diagnoses each year in the United States being documented. Risk however, is sustained in those who have been exposed to asbestos. Even those exposed many years ago are potentially at risk for the development of malignant peritoneal mesothelioma. Latency between exposure to asbestos and the development of peritoneal mesothelioma symptoms can be anywhere from 20-50 years. Misdiagnosis is also common because peritoneal mesothelioma symptoms closely mimic minor stomach/abdominal discomfort and hernia. Nevertheless, those with clear asbestos exposure history should be aware of the disease and speak with their doctor or cancer specialist if they believe they be experiencing symptoms related to mesothelioma.

How is Peritoneal Mesothelioma Treated?

Prognosis of mesothelioma patients is poor, and peritoneal mesothelioma patients are no exception. Most peritoneal mesothelioma treatment regimens for patients include palliative methods such as mesothelioma chemotherapy and radiation therapy. However, if the disease is diagnosed in its earlier stages, such patients as those diagnosed with stage 1 mesothelioma, these individuals  may be eligible for surgical resection of the disease, which could potentially add years to initial prognoses.

Surgery is possible for patients diagnosed with earlier-stage disease. Some surgical options include pneumonectomy, extra-pleural pneumonectomy, and palliative procedures such as thoracentesis or pleurodesis. Pneumonectomy and extra-pleural pneumonectomy are extensive procedures that involve there removal of the affect lung and surrounding body structures. Certain physicians, including Dr. David Sugarbaker of the International Mesothelioma Program at Brigham and Women’s Hospital in Boston, MA, have become extremely well-versed and experienced in the surgical treatment of malignant mesothelioma. In many cases, surgical treatments for mesothelioma will be coupled with chemotherapy or radiation therapy regimens.

Chemotherapy is the most common treatment for mesothelioma disease. Currently, there is only a single chemotherapy regimen (Alimta (pemetrexed) in conjunction with Cisplatin) approved by the Food and Drug Administration as a prescribed therapy for the treatment of malignant pleural mesothelioma. There are however, dozens of clinical trials being conducted for mesothelioma patients experimenting with new drugs, including gemcitabine, Navelbine, Onconase, and others for the treatment of malignant peritoneal mesothelioma.

How is Peritoneal Mesothelioma Diagnosed?

Mesothelioma doctors may suspect peritoneal mesothelioma if the patient complains of stomach, chest, or abdominal pain. Suspicious hernias may actually be a pleural effusion caused by peritoneal tumor growth. Misdiagnosis is common and patients will likely undergo multiple imaging scans and a diagnostic biopsy before an official diagnosis is made.

Diagnostic procedures in which fluid is extracted from the peritoneum for lab testing are the only way to conclusively diagnose peritoneal mesothelioma. Samples will be examined for the presence of malignant cells. Once malignant cells are detected, further testing will be needed to classify these cells as malignant mesothelioma.

What are a patient's options?

Patients of peritoneal mesothelioma may be eligible for financial compensation if they were harmfully exposed to asbestos. Industrial exposures were common and those exposed have collected compensation to finance high treatment costs. For additional information on your legal rights of mesothelioma please fill out the brief contact form on this page.

Source
PubMed Central
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1994863

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Pericardial Mesothelioma

Malignant pericardial mesothelioma is a type of cancer that originates in the mesothelium, a thin wall of cells that surround the body's organs and internal body structures. Pericardial mesothelioma originates in the lining of the heart. Other locales of the disease are malignant pleural mesothelioma, which occurs in the lining of the lungs and malignant peritoneal mesothelioma, which occurs in the abdomen wall. Pericardial mesothelioma is the rarest of these malignancies and accounts for only an estimated 10 percent of all mesothelioma incidences annually.

What Causes Pericardial Mesothelioma?

Pericardial mesothelioma is an asbestos cancer, meaning it's only known cause is asbestos exposure. Asbestos is a naturally occurring, but toxic, mineral that was used in industrial capacities. While the precise route by which microscopic asbestos fibers reaches the pericardial lining is not known, mesothelioma doctors surmise that inhaled asbestos fibers are absorbed into the bloodstream and become entangled in the heart's lining as the blood processes through the heart. Malignant mesothelioma occurring in other parts of the body, such as in the pleura or peritoneum, can also metastasize to the pericardial lining.

How is Pericardial Mesothelioma Treated?

Prognoses are poor in cases of pericardial mesothelioma, just as nearly every mesothelioma prognosis is. However, several treatment options exist to help patients manage the disease and maintain comfort. Chemotherapy and radiation therapy are the most likely mesothelioma treatment options for patients of this disease. Mesothelioma surgery is typically not an option because of the location of the disease and the risk of grave damage to the tumor area.

How is Pericardial Mesothelioma Diagnosed?

Physicians will often suspect pericardial mesothelioma diagnosis if the patient has trouble breathing, shortness of breath, or chest pain. A comprehensive diagnostic and biopsy process will be undergone through use of multiple body imaging scans.

What are a Patient's Options?

Patients of pericardial mesothelioma may be eligible for financial compensation if they were wrongly exposed to asbestos. Anyone who worked with asbestos products is potentially at-risk and should fill out the brief form on this page to receive additional treatment and legal information.

Source
PubMed Central
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=325154

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Pleural Mesothelioma

In most instances, pleural disease is not considered fatal but it does have the ability to impair lung function and it does confirm that a person has sustained significant asbestos exposure and could be at a higher risk for developing more severe asbestos cancer. If you have been diagnosed with pleural disease it is important to preserve your legal rights.

 
However, pleural plaques can lay the groundwork for pleural mesothelioma, which is an extremely aggressive cancer known only to be caused by asbestos exposure. Pleural mesothelioma originates in the pleura but quickly spreads to the outer chest wall, abdomen, and heart. Pleural mesothelioma is typically fatal within 1 year of diagnosis. However, early recognition of risk factors, like asbestos exposure will typically lead to early detection of the cancer. Those whose disease is discovered early enough will likely be much more eligible for life-sustaining and bettering treatments. Patients who receive an early mesothelioma diagnosis may be eligible for surgical resection of the cancer, which can extend life years beyond that of typical mesothelioma patients.

Pleural mesothelioma is often seen in people who have been exposed to high levels of asbestos on the job. It sometimes takes 10 years or more for changes to appear that are indicative of pleural disease which affects the thin membrane layer in the chest. These differences can include a thickening or calcification of the pleural lining and is usually diagnosed as pleural plaques, pleural thickening and pleural calcification.

There are ways for patients to manage the disease through mesothelioma treatment, including traditional mesothelioma radiation and chemotherapy methods which can ease symptoms of the disease and make the cancer much more manageable. In patients where a diagnosis is made of early stage disease, mesothelioma surgery can extend the survival rate far beyond previous levels in untreated disease.

Pleural Mesothelioma Treatment

Nearly all patients diagnosed with pleural mesothelioma are able to receive some form of treatment for their illness. While there is currently no cure for mesothelioma, patients have been able to extend survival rates through advanced mesothelioma treatment regimens currently being developed at mesothelioma clinics and cancer centers across the United States.

Pleural Mesothelioma Surgery

Surgical resection is difficult in pleural mesothelioma patients when the disease is diagnosed in later stages because at that time the tumor has typically metastasized to other areas of the body like the abdominal cavity and lymph nodes. However, in early stage diagnoses, surgery can absolutely be utilized to slow the advance of mesothelioma disease.

Common surgical procedures utilized in the management of malignant mesothelioma are pneumonectomy and extrapleural pneumonectomy. Pneumonectomy is a general procedure utilized not only in patients of malignant mesothelioma, but also those battling lung cancers or related lung conditions. Pleurectomy involves the removal of a portion or the entire affected lung in patients. Extrapleural pneumonectomy is a more comprehensive procedure that is more tailored to mesothelioma patients. Extrapleural pneumonectomy involves the removal of the entire affected lung, the pleura, the diaphragm, and the pericardium, which is the mesothelial lining that surrounds the heart cavity.

Pleural Mesothelioma Chemotherapy

Chemotherapy is likely the most prevalent treatment utilized by patients of malignant pleural mesothelioma. While several different chemotherapy drugs have been utilized to varying degrees of effectiveness for the management of malignant pleural mesothelioma, only one has been approved by the Food and Drug Administration as a prescribed therapy for the treatment of malignant pleural mesothelioma. A combination of Alimta (Pemetrexed) and Cisplatin is currently the only cocktail prescribed en masse for the general treatment of pleural mesothelioma. However, several other clinical trials are currently active attempting to determine the effectiveness of other drugs including Gemcitabine, Navelbine, and Onconase.

Pleural Mesothelioma Radiation Therapy

Radiation therapy has been utilized in the treatment of many types of cancer and pleural mesothelioma is no different. Often, radiation is not able to manage cancer by itself so it is combined with either surgery, chemotherapy, or both to augment the treatment plan as a whole. Radiation therapy for pleural mesothelioma utilizes external beam radiation to mutate tumor cells within the body and slow their growth and spread.

Alternative Therapy for Pleural Mesothelioma

A growing school in cancer care is integrative approaches in the treatment of cancer. Integrative oncology utilizes not only the conventional therapies discussed above, but also untraditional therapies such as acupuncture, massage, and reflexology to assist the patient in managing pain, anxiety, and restlessness. Patients battling pleural mesothelioma have effectively utilized alternative therapies such as these to increase the effectiveness of their treatment program overall. Generally, patients who are able to withstand the difficult side-effects of more potent chemotherapy and radiation treatments will be best able to extend their mesothelioma prognosis. Patients of pleural mesothelioma who have utilized alternative therapies have been able to do just that. However, most of these therapies are preferential and will depend on the health of the patient as to whether or not they will be able to engage in them. As will anything, patients should seek the consultation of their physician or cancer specialist before engaging in any alternative therapy.

What Causes Pleural Mesothelioma?

Pleural mesothelioma is known only be caused by exposure to asbestos. Asbestos is a naturally occurring and microscopic mineral that was used for hundreds of years in a number of different industrial compounds. Asbestos fibers are extremely durable, but also extremely difficult to expel from the body once introduced to the internal tissue.

Upon inhalation, asbestos fibers will lodge on the outer layers of the lung tissue and within the pleura, a thin membrane of mesothelial cells which lines the chest cavity. This lining allows for the free movement of the body’s internal body structures because it provides a special lubrication to the surface of these structures. The pleura, like other mesothelial membrane, is a delicate structure and even microscopic asbestos fibers can cause pleural plaques to form on its surface and eventually, pleural mesothelioma tumor cells. Generally, it takes many years between asbestos exposure and the development of adverse health complications, as the fibers will slowly irritate and inflame the internal tissue until symptoms appear.

Many of those exposed to asbestos have successfully received compensation from asbestos product manufacturers for injuries and illnesses such as pleural mesothelioma. If you believe you were wrongfully exposed to asbestos and have developed an asbestos-related health complication, we urge you to complete the brief form on this page. We’ll rush you a complimentary mesothelioma and asbestos exposure information packet detailing advancements in the treatment of pleural mesothelioma, top doctors and cancer centers, and mesothelioma attorney options you may have.

Don't Let Time Get in the Way!

Don't let time prevent you from taking legal action if you have been diagnosed with malignant pleural mesothelioma as a result of asbestos exposure. Every state establishes set timeframes for filing lawsuits for an asbestos related injury. These timeframes are also known as the state statutes of limitation. The deadlines established in the statutes are fixed so it is important to consult with a legal professional soon after the onset of an asbestos related illness to determine what, if any action may be appropriate.

Source
American Cancer Society - Detailed Guide: Malignant Mesothelioma - What Is Malignant Mesothelioma?
http://www.cancer.org/docroot/CRI/content/CRI_2_4_1X_What_is_malignant_mesothelioma_29.asp

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Mesothelioma Law

Asbestos law dates back to 1929 in the United States. However, by the 1970s, the evidence of the material as a substantial health hazard had become abundantly clear. This changed the way asbestos claims were viewed.
In the early 1980s, the some plaintiffs started receiving multi-million dollar jury awards and settlements for asbestos claims. This caused the Manville Corporation, formerly the Johns Manville Corporation, a Fortune 500 company, to file for bankruptcy protection. The Manville Corporation was an asbestos manufacturer that had thousands of lawsuits brought against the company related to the health effects of the product.
Court documents showed that the Manville Corporation had a long history of hiding evidence of the harmful effects of asbestos from its employees and the public. At the time it went bankrupt, it was the largest U.S. company ever to file for bankruptcy protection.
New laws and the changing landscape caused asbestos manufacturers to alter the way they operated. Many large manufacturers diversified their products, produced substitutes, sold off subsidiaries, or started asbestos removal businesses. Due to the health hazards caused by asbestos and resulting lawsuits, the removal of the product became big business.
By the early 1990s, more than half of the top 25 largest asbestos manufacturers had filed for bankruptcy protection. This shielded them from creditors. Bankruptcy protection caused plaintiff lawyers to seek new avenues of relief for the clients, targeting companies that used it in their products. Large companies that have seen significant asbestos litigation include the Boeing Company, the Ford Motor Company, Deere & Company, and the Sears Roebuck & Company.
The U.S. Supreme Court has consistently upheld the rights of individuals to pursue asbestos claims. Two large class action asbestos settlements came before the Court in 1997 and 1999. The Court rejected both, as they would have excluded future claims.
Legislation has been proposed to reduce the amount of asbestos litigation in the United States. However, still today the U.S. Congress has failed to act on a 2005 bill entitled "Fairness in Asbestos Injury Resolution Act of 2005". If passed, the Act would establish a $140 billion trust fund for victims. The Act would limit employer liability. In the meantime, federal and state courts have thousands of asbestos cases on the docket. Due to the delayed onset of the disease, it is predicted the number of asbestos cases will continue to increase in the coming years.

Mesothelioma law is complex. Learn more about asbestos and the stages of mesothelioma at http://www.stagesofmestothelioma.org.

Article Source: http://EzineArticles.com/?expert=Jason_F._Nelson

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Mesothelioma Types

There are Types of Mesothelioma:
  
Pleural Mesothelioma - affects the chest and lungs

Malignant pleural mesothelioma often originates within the chest cavity and can, at times, involve the lung. This particular form of mesothelioma can metastasize to numerous organs in the body - even the brain - and tends to do so more frequently than not.

Pleural mesothelioma is not always easily detectable. Frequently, in the early stages of the disease, such as stage 1 mesothelioma, symptoms may be mild. Patients usually report pain in one area of the chest that never seems to go away, weight loss and fever. Occasionally, other symptoms are more severe and include problems with breathing due to fluid build up in the chest. A CT Scan of the chest area has proven to be the best test for identifying how far along the disease has progressed.

Frequently serum markers are used to diagnose of various forms of cancer. Mesothelioma cannot be diagnosed using this method as no serum markers currently exist. If high levels of hyaluronic acid are present it may be possible to distinguish mesothelioma types from other types of cancer or to determine the effectiveness of a treatment protocol.

The mesothelioma survival rate for patients diagnosed with pleural mesothelioma typically is not high. Patients typically do not live beyond seventeen months from the onset of symptoms. Only 8% of those with a mesothelioma diagnosis will live three to five years from the onset of mesothelioma symptoms.

Pericardial Mesothelioma - affects the heart

Pericardial mesothelioma is the least common form of mesothelioma. Pericardial mesothelioma, as the name suggests, involves the heart. This rare type of mesothelioma cancer invades the pericardium, the sac that surrounds the heart. As the cancer progresses, the heart is not able to deliver oxygen as efficiently to the body causing further decline in health at an increasingly rapid rate. The symptoms most commonly associated with pericardial mesothelioma mimic those of a heart attack: nausea, pain in the chest and shortness of breath.

Peritoneal Mesothelioma - affects the abdomen

Peritoneal mesothelioma originates in the abdomen and will frequently spread to other organs in area including the liver, spleen or bowel. Severe abdominal pain is the most common complaint that patients present to mesothelioma doctors. There may also be a discomfort level with fluid build up in the abdomen as well. Other symptoms of peritoneal mesothelioma may include difficult bowel movements, nausea and vomiting, fever and swollen feet.

The survival rate is even worse for those diagnosed with peritoneal mesothelioma will patients typically surviving only ten months from time that they first started experiencing the symptoms noted above.

Malignant Mesothelioma
Malignant mesothelioma is an uncommon form of cancer and of all asbestos related diseases, the most serious. The symptoms associated with the disease make it difficult for doctors to diagnose. Often, by the time that a proper diagnosis is made, the disease has progressed to a point where patients do not respond well to treatment therapy. Malignant mesothelioma is caused almost exclusively by the inhalation of airborne asbestos particles. Another unique factor associated with the disease is that there can be a long latency period between the time of asbestos exposure and the actual manifestation of the disease in the form of malignant mesothelioma.

Benign Mesothelioma

Benign mesothelioma, or non-malignant mesothelioma, is much easier to treat than the malignant form of the cancer and can be treated successfully in many cases.

Mesothelioma in Uncommon Sites

A form of cardiac cancer that is rarely seen involves the pericardium. Tumors associated with this type of mesothelioma are not easily detectable and patients presented with this diagnosis tend to have a very low survival rate. There have also been reports of mesothelioma involving ovaries in women and the scrotum in men. Mesothelioma treatment for all of these rare forms of the disease will vary depending on what stage a patient has progressed to but in most all cases the projected outcome is not favorable.

Sources

Mesothelioma Research Foundation of America - Types of Mesothelioma
http://www.mesorfa.org/about-meso/types.php
Cancer Research UK - Types of Mesothelioma
http://www.cancerhelp.org.uk/help/default.asp?page=4398

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Mesothelioma law resources

Mesothelioma is a deadliest form of cancer that has developed via the exposure of asbestos. Mesothelioma develops the malignant or cancerous cells in the mesothelium, which is the cell which protects various internal organs in our human body. The types of mesothelioma are pleural mesothelioma, peritoneal mesothelioma and pericardial mesothelioma. The mesothelioma law resources provide you information on the disease, mesothelioma lawsuits, mesothelioma doctors, and mesothelioma lawyers and other legal resources.

Mesothelioma law resources help a person who has developed the disease in the exposure of asbestos providing the legal resources and further steps for the mesothelioma settlements. Mesothelioma is the disease that damages the cells which surround various internal organs like the heart, lungs and the abdomen. It develops gradually within the human body by damaging the cell lining which covers these organs. Inhaling the asbestos materials from the workplace is a major cause for the development of mesothelioma.
Shortness of breath and chest pain developed due to the accumulated fluid in the pleura are the major symptoms of pleural mesothelioma. Bowel obstruction, abnormality in the clotting of blood, fever and anemia are few of the peritoneal symptoms. The common symptoms of the pericardial mesothelioma are persistent coughing, palpitations, shortness of breath and chest pain.

The person who has developed mesothelioma has to be diagnosed immediately when these symptoms are seen. If the presence of mesothelioma is confirmed, immediate treatment is recommended. The person may seek lawsuit assistance as the legal compensation for the mesothelioma through the exposure of asbestos. A legal medical expert can help you in providing the information of the disease that has developed through the exposure of asbestos. This would help you in receiving rightful and fair compensation.

There are several law firms that offer you the best service. One has to assess whether the law firm to be selected is a good one and certified applicable under the State Bar Association. A perfect lawyer can be approached from any top law firm who has a well specialized track record in dealing with mesothelioma cases. A lawyer with a good track record can offer you with the best compensation for mesothelioma from the irresponsible firms that have failed to protect you from the exposure of asbestos.

Mesothelioma Laws provides detailed information on Mesothelioma Diagnosis, Mesothelioma Law Firms, Mesothelioma Law Resources, Mesothelioma Law Services and more. Mesothelioma Laws is affiliated with Failure To Diagnose Mesothelioma Lawsuits.

Source

http://EzineArticles.com/?expert=Elizabeth_Morgan

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Mesothelioma Prognosis

When an individual is diagnosed with mesothelioma or any other kind of cancer, one of the first questions they will have is “How long do I have to live?” This is a scary question - and a hard one to ask - but one for which most cancer patients will eventually seek an answer.
It is often very difficult for oncologists and members of a patient’s medical team to give a definitive answer to this query. Indeed, every case is different and cancer can be an unpredictable disease. Sometimes, cases that look hopeless turn out to be not so bleak. In other cases, cancers that don’t look so bad progress quickly and result in an untimely death.
Overall, the prognosis has been rather grim for meso patients during these past few decades. Malignant mesothelioma is extremely aggressive and has a long latency period. Hence, cases are usually not detected until the disease has reached the advanced stages of cancer. As a result the prognosis for such patients is often not favorable; the mesothelioma survival rate following diagnosis is usually just a year or two. That doesn’t mean, however, that there won’t be exceptions and that this dour outlook will not change in years to come, especially as more and better treatments are developed.

Determining Prognosis

Currently, a number of different issues determine the mesothelioma patient’s prognosis. These include:

• Type - Mesothelioma is classified as one of three types, depending on the tissues involved. The epithelial type accounts for about 50 percent of all cases, sarcomatoid mesothelioma is seen in 15 percent of diagnosed patients, and 35% have the mixed type of the disease. Those with epithelial mesothelioma have a better survival rate than the other types.
• Location - Mesothelioma is also classified on the basis of location. For example, pleural mesothelioma, which attacks the lining of the lung, is the most common, accounting for approximately 8o percent of all cases. Those with this type of cancer have the best rate of survival. Peritoneal mesothelioma, found in the lining of the abdomen, is the next most common and is diagnosed in about 10 -15 percent of mesothelioma victims. It is generally harder to treat. Less common types are very difficult to treat, including pericardial and testicular mesothelioma.
• Stage of the disease - The prognosis for mesothelioma cancer depends on how early the disease is diagnosed and how soon treatment can begin. Because of the disease’s extended latency period, it is often not diagnosed until it has reached Stage 3 or 4, when mesothelioma symptoms finally appear. Sadly, many of these symptoms are common to a wide range of respiratory diseases including many that are less serious, like the flu or pneumonia. This often results in misdiagnosis.
• Metastasis - When a mesothelioma diagnosis is finally made, oncologists will often find that the cancer has spread - or “metastasized” - from the location of the primary tumor - usually the pleura - to other parts of the body, often to the nearby organs as well as the lymph nodes. The extent of the metastases will determine what type of treatment is recommended as well as the prognosis.
• General health of the patient - Simply put, younger and stronger patients with mesothelioma live longer than those of advanced age who have extant health problems. Seniors are often dealing with issues like heart disease, diabetes, and high blood pressure, making mesothelioma surgery as well as traditional cancer treatments much more risky and severely limiting treatment options. 

 

Survival Rates

Most survival rates for cancer are quoted in regards to what is commonly known as the relative five-year survival rate. This indicates the number of patients who are still alive five years after they are diagnosed with the disease. Currently, the five-year survival rate for meso victims is just 10 percent. Though this seems like a grim number, it is indeed higher than it was about 10 years ago and much higher than it was 20-30 years ago.
The current one-year survival rate for mesothelioma patients is about 40 percent. This has also increased significantly in the last 10 years. Unfortunately, however, the prognosis for most mesothelioma patients remains poor overall. Many still die less than a year after diagnosis, with the average survival rate being 10-11 months, according to the American Cancer Association.

Improving the Mesothelioma Prognosis

During the last decade, the plight of mesothelioma sufferers has gained more attention and more research dollars have been funneled towards the study of this disease and the discovery of new and novel drugs and treatments to provide more hope of a better prognosis for the mesothelioma sufferer.
Scientists have been working on new tests that strive to diagnose the disease at an earlier stage. For example, the Mesomark® assay is a simple blood taste that measures the rate of Soluble Mesothelin-Related Peptides (SMRP) in the blood. This biomarker is released by mesothelioma cells into the bloodstream and SMRP can be elevated for many years before symptoms appear and an actual diagnosis of the disease is made. This tool for early diagnosis could potentially save hundreds of lives.
Treatments with new chemotherapy drugs like Alimta® and procedures that deliver more targeted radiation to the tumor have also helped to add to a mesothelioma patient’s life expectancy. In addition, experimental treatments such as immunotherapy, gene therapy, and photodynamic therapy have shown some success in treating this difficult disease.
Each new step in the field of mesothelioma research improves the mesothelioma prognosis little by little and provides additional hope for mesothelioma-affected individuals and their loved ones.

Source

http://www.cancer.org/Cancer/MalignantMesothelioma/OverviewGuide/malignant-mesothelioma-overview-survival-rates

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Get to a Mesothelioma Law Firm in Time to Claim the Compensation

It is better to take resort to a mesothelioma law firm or mesothelioma lawyers as soon as mesothelioma disease is diagnosed clinically. There are many essential and mandatory legal factors like time bar to file the suit, the time and duration for exposure, the damage caused due to working in a particular industry or damage caused by some arbitrary act on the part of the patient in his early life etc. As determining the applicability of all these factors are part of specialized knowledge and professional expertise so it is always wise to leave the decision in the hand the mesothelioma lawyers or mesothelioma law firm. Sometimes to find exactly how much relevance the alleged exposure does have with the claim for compensation, the mesothelioma law firm may even hire a private investigator to look into the matter.

There are many law firms which exclusively deal with only mesothelioma cases. Such kind of law firms keep mesothelioma lawyers who do only deal with the cases relating to compensation claim in case mesothelioma disease is diagnosed in a patient. There are many companies which to up size profit, compromise the safety of the workers and make them work in dusty environment with little or no protection.

This irregularity is more often in asbestos industries and stone- crusher industries where the workers are exposed to hazard more expansively than anywhere. With each breathing they intake the microscopic dust particle which do not come out with exhalation but stick to the wall of lungs. After long time normally after years of working in that environment, when the body gradually weakened the hazard shows itself. So, it is probably an exception among the diseases, in which the harm is perceived when already it is too late to prevent. Once, lungs and heart thus weaken, automatically the patient is faced with considerable decrease in his energy to work and ironically, to earn. In such situation, mesothelioma law firm and mesothelioma lawyers become of great help. It is always pretty advantageous to the patient to take resort to legal advice from a reputed mesothelioma law firm in or around his locality, because the profit to the patient is from both sides, in winning or losing.

During seeking legal advice in such cases the patient or any party on the patient's side does not need to pay any fees at the first instance. The fee is only claimed when the compensation is awarded to the patient or any party legally authorized. A percentage is charged by the mesothelioma lawyers or mesothelioma law firm who was engaged for the job. Whatever measures or options be taken by the mesothelioma law firm, it is not usually chargeable unless the case is won. So, it is advisable that whenever a disease of mesothelium called mesothelioma is diagnosed then it is better to avail legal advise regarding claiming of compensation. Unlike other law suits particularly in mesothelioma cases it is never a loss to seek a legal advice as there is no need to pay unless the patient is paid at first, in form of compensation.

For reliable assistance about mesothelioma legal issues, one can online visit mesothelioma law firm at mesotheliomalawyersfirm.com to avail professional advice from board of mesothelioma lawyers.

Source:

http://EzineArticles.com/?expert=Corwin_Knight

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Mesothelioma Diagnosis

Mesothelioma medical professionals diagnosis

If you believe that you may have mesothelioma, a qualified medical professional will use a variety of diagnostic tests and methods to confirm the presence of the disease.

1. Medical history review and exam
The first step that mesothelioma doctors will take in evaluating an asbestos related disease is to obtain a full medical history to determine the level and severity of mesothelioma risk factors and presenting mesothelioma symptoms. This interview will look consider among other things, where asbestos exposure occurred, the length of exposure and the amount of asbestos that you were exposed to.
In addition, he/she will perform a medical exam to look for signs and symptoms of various types of mesothelioma. For example, if pleural mesothelioma is suspected the doctor will look for fluid in the chest, peritoneal mesothelioma often shows fluid in the abdomen and pericardial mesothelioma presents with fluid in the area of the heart.

2. Diagnostic imaging tests
Chest x-rays are used to identify abnormalities in the lungs including unusual thickening, mineral deposits and fluid in the chest area. If these conditions are present then it may be evidence that mesothelioma has developed.
Diagnostic image tests like x-rays, CT scans and MRI's are useful in determining more information about the cancer including how far it is progressed. Each method provides another piece of information to your doctor to assist in making an accurate diagnosis. CT scans are capable of providing images of the same location from many different angles. MRI technology uses magnetic fields rather than x-ray to provide additional views.

3. Testing fluid and tissue samples
If fluid build-up in the chest, abdomen or heart area is present, your doctor may want to obtain a sample. To accomplish this he/she will use a long needle to obtain fluid from the target area. The fluid will then be sent to the lab for analysis.
A bronchoscopy procedure may be recommended for patients who are suspected of having pleural mesothelioma. For this medical test, a soft tube illuminates the trachea and bronchi to determine if any masses are present in the airways. If deemed necessary, the technician my take sample of tissue that appears to be abnormal for further testing.
If lymph node involvement is suspected which is common with asbestos lung cancer, patients may also undergo a mediastinoscopy. This procedure is similar to a bronchoscopy in that a soft tube enters the body under the chest bone and illuminates the chest area. In this way, the surgeon can examine lymph nodes for abnormalities, check to see how far disease may have progressed and when necessary help diagnose lung cancer vs. mesothelioma.
Diagnosing mesothelioma is never easy. Fluid build up alone in the chest, belly or heart regions is not enough to confirm a diagnosis. Tissue samples obtained from biopsy procedures are also difficult to discern because mesothelioma cancer cells often resemble other types of cancer. For this reason, specialized laboratory procedures are often employed to identify certain chemicals that are known to exist with mesothelioma and high powered laboratory equipment is used to examine the smallest details of cancer cells to confirm that mesothelioma is present.

Source
National Cancer Institute - Mesothelioma: Questions and Answers
http://www.cancer.gov/cancertopics/factsheet/Sites-Types/mesothelioma

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Mesothelioma Symptoms

The warning signs of mesothelioma

Mesothelioma is difficult to diagnose because the early signs and symptoms of the disease can be subtle at best. Symptoms are all too frequently ignored or dismissed by people who are inclined to attribute them to common every day ailments. Sometimes patients live with symptoms for up to 6 months before being diagnosed but usually the symptoms are present for two to three months prior to mesothelioma diagnosis.

About 60% of patients diagnosed with pleural mesothelioma experience lower back pain or side chest pain and there are frequent reports of shortness of breath. Lower numbers of people may experience difficulty swallowing, or have a persistent cough, fever, weight loss or fatigue. Symptoms to also consider are muscle weakness, loss of sensory capability, coughing up blood, facial and arm swelling and hoarseness.

Peritoneal mesothelioma originates in the abdomen and as a result, symptoms often include abdominal pain, weight loss, nausea, and vomiting. In the event that there is a hernia present, fluid build up may occur in the abdomen as well. Anyone previously exposed to asbestos displaying any of these symptoms should seek medical attention from mesothelioma doctors who specialize in treating mesothelioma like Dr. David Sugarbaker.

Source
Medicine.Net - Mesothelioma
http://www.medicinenet.com/mesothelioma/article.htm

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Carbon Nanotubes

Do you know about nanotechnology? Nanotechnology is the emerging scientific study related to the use of small, thin, carbon-based materials known as nanotubes. A plethora of products featuring nanotubes are becoming more and more widely used. These products range from technologically advanced items utilized by NASA to everyday items used in the home. Nanotubes are increasingly popular due to their light weight and supreme strength, which is said to be stronger than steel.

As the variety of uses for nanotubes increases, researchers continue to do studies and tests related to the consequences of nanotube use. Current research states that exposure to the thin, lengthier version of carbon-based nanotubes may lead to the development of pleural mesothelioma, a deadly form of cancer that affects the lining of the lungs and has no known cure. Scientists claim that there is no cause for immediate concern, but that further testing related to nanotube exposure and the onset of mesothelioma is crucial. As with exposure to asbestos, nanotubes are only potentially dangerous if the tiny fibers are inhaled, putting manufacturers, lab researchers, suppliers, and other professionals who may handle nanotubes at the most risk.

What Kinds of Products Contain Nanotubes?

Carbon-based nanotubes are utilized in a vast array of items, including sports gear, automobile parts, electronic equipment, advanced medical tools, and items, such as space shuttle parts, currently in development by NASA. For your reference we have prepared a comprehensive list of products that may contain nanotubes.

What Risks Are Associated With Nanotube Exposure?

Currently, scientists and researchers assure the public that there is no immediate cause for concern related to nanotube exposure. The risk of developing pleural mesothelioma is greatest if the tiny carbon-based fibers of nanotubes are inhaled, much like the risk associated with inhalation of asbestos. However, those who handle nanotubes in the manufacturing and testing phases are at risk if they do not utilize appropriate breathing apparatuses and other necessary equipment.

Source
EmaxHealth - Carbon Nanotubes May Cause Mesothelioma Cancer
http://www.emaxhealth.com/111/22496.html

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Mesothelioma Causes

The main cause of the occurrence of mesothelioma

Asbestos exposure is the main cause of mesothelioma. Asbestos fibers that are inhaled through the mouth and nose may eventually become embedded in the lining of the lungs, causing damage and resulting in mesothelioma lung cancer or asbestosis (scar tissue formation in the lungs). It has also been found that swallowing asbestos fibers could contribute to a form of mesothelioma originating in the abdomen called peritoneal mesothelioma.

Mesothelioma cancer generally results from occupational exposure but there are instances of environmental exposure to asbestos that can cause mesothelioma disease. Oftentimes second hand exposure of a family member to an asbestos workers dirty work clothes can result in that family member having a mesothelioma diagnosis. Asbestos insulation workers appear to have the highest death rate. One study reports that almost six percent of asbestos workers fall victim to mesothelioma or experience mesothelioma symptoms and asbestos insulation workers are over 300 times more likely to die from mesothelioma than the general public.

Sources

Cancerbackup - Causes of mesothelioma
http://www.cancerbackup.org.uk/.../Causes

eMedicineHealth - Mesothelioma Causes
http://www.emedicinehealth.com/mesothelioma/page2_em.htm

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Mesothelioma

The most serious of all asbestos-related diseases is malignant mesothelioma. Although uncommon, mesothelioma cancer is no longer considered rare. Making a correct mesothelioma diagnosis is particularly difficult for doctors because the disease often presents with symptoms that mimic other common ailments. There is no known cure for mesothelioma, but treatments such as mesothelioma radiation and chemotherapy have helped to improve the typical mesothelioma prognosis.

The cavities within the body encompassing the chest, abdomen, and heart are surround by a membrane of cells known as the mesothelium. Mesothelial cells assist in general organ functions.

The mesothelium is particularly important to organs which are commonly in motion, such as expansion or contraction of the lungs, stomach, or heart. Lubrication from the mesothelial cells allows free range of motion within the body. The mesothelium of the chest, abdomen, and cardiac cavity are called the pleura, the peritoneum, and the pericardium, respectively. Each of these groupings of mesothelial cells are extremely critical to the functions of the body structures which they encompass.

Malignancies (cancerous tumors) occurring within the mesothelial membranes are known as malignant mesothelioma, or simply mesothelioma. Benign tumors of the mesothelium are known to occur, but are much rarer than the more common mesothelioma cancer.

While tumors of the mesothelium were first recognized in the late 18th century, it was not until the middle of the 20th century that this particular cancer was studied and examined with more detail. It was at this time where suspicions of the cancer’s causal relationship with asbestos exposure became more substantiated. A joint study through the Department of Thoracic Surgery at the University of the Witswaterand/Johannesburg General Hospital in South Africa provided the most compelling evidence of the nexus between asbestos exposure and the development of pleural mesothelioma.

Incidence of mesothelioma is still quite rare, with only 2,500-3000 diagnoses in the United States each year. There was a spike in reported diagnoses between 1970 and 1984, which has been attributed to the latency period between diagnosis and the height of industrial exposures- which occurred roughly 40-60 years prior to this time. Exposure was common in nearly all industries but was particularly common in the WWII-era military industrial cycle, including Navy Shipyards.

Although this cancer is much more common in men over the age of 60 (largely attributed to the industrial exposures within male-dominated industries), mesothelioma in women and children has been described as well. Mesothelioma causes for diagnosis in women and children are mainly attributed to secondary exposure to asbestos, as it was not uncommon for men to bring asbestos back into the home on their body or clothing if proper cleaning facilities were not available on site.

There are three recognized mesothelioma cell-types. Between 50 and 70% of all mesotheliomas are of the epithelial variety. While prognosis is generally poor, these are considered less aggressive than mesotheliomas of the sarcomatoid and biphasic variety, which comprise the remainder of diagnoses. Mesothelioma treatment options for each type of diagnosis are essentially the same, depending on stage at diagnosis and overall patient health.

Pleural mesothelioma (affecting the lung’s protective lining in the chest cavity) represents about three quarters of all mesothelioma incidence. Peritoneal and pericardial mesotheliomas, affecting the abdominal and cardiac cavities comprise the remainder. Testicular mesothelioma is extremely rare and is typically presents with metastases of the peritoneal variety.

Mesothelioma Cancer Treatments

Mesothelioma, while certainly an aggressive disease, is a treatable malignancy. While there is no cure for mesothelioma, treatment options including surgery, chemotherapy, and radiation therapy are available for many patients. While a combination of Alimta® and Cisplatin is currently the only FDA approved chemotherapy regimen, several clinical trials are currently in progress utilizing other drugs including Gemcitabine and Onconase, with many showing dramatically improved results in certain cancer patients.

Radiation therapy is also utilized, but typically in conjunction with other treatment methods like surgery and chemotherapy. Surgical resection of mesothelioma is possible in early-stage-diagnosed patients. Aggressive surgeries such as extrapleural pneumonectomy can extend survival rates far beyond previously-thought timeframes. Diagnostic and palliative surgeries such as pleurocentesis and pleurodesis are also common in patients of malignant mesothelioma cancer.

Alternative therapies have also been used effectively by many mesothelioma patients to assist in managing symptoms of the disease and conventional treatments. These treatments are mainly preferential but can be extremely valuable to many patients.


Mesothelioma Cancer Diagnostic

Mesothelioma can be a difficult malignancy to diagnose because the symptoms and pathology of the disease closely resemble other respiratory conditions. For this reason, misdiagnosis is not uncommon in mesothelioma patients. Symptoms of mesothelioma include chest pain, chronic cough, effusions of the chest and abdomen, and the presence of blood in lung fluid.

Diagnostic surgeries, including a biopsy, will typically be required to determine the type of malignant cells that are present in the body. Typically a body imaging scan, including a magnetic resonance image (MRI) or computer topography (CT scan) will be required to determine the extent and location of the disease.

Mesothelioma patients are generally referred by their personal physicians to one of the many renowned mesothelioma doctors in the United States. These oncologists are well versed in the disease behavior and pathology and are the most familiar with cutting-edge mesothelioma treatment options. Dr. David Sugarbaker of the Brigham and Women's Hospital, an extension of Harvard University and the Dana Farber Cancer Institute in Boston, MA, is at the forefront of mesothelioma treatment through the International Mesothelioma Program.


Causes of Mesothelioma Cancer

Mesothelioma is known only to be caused by exposure to asbestos, though cases have been documented in children or other individuals with no asbestos history. Asbestos is a microscopic and naturally-occuring mineral that lodges in the pleural lining of the lungs and the peritoneal lining of the abdominal cavity. In most cases, several years will pass (up to 60) before mesothelioma develops in those who had been exposed to asbestos.

In many cases, those diagnosed with mesothelioma who are known to have been exposed to asbestos may be eligible for financial compensation from asbestos manufacturers for their illness. Those who have been diagnosed with mesothelioma and were exposed to asbestos should fill out the brief form on this page. We'll rush you a complimentary mesothelioma and asbestos exposure information kit detailing new mesothelioma treatments, active clinical trials, top doctors, as well as how to obtain compensation for asbestos-related health conditions like mesothelioma.

Sources:
National Cancer Institute – Malignant Mesothelioma
http://www.cancer.gov/cancertopics/types/malignantmesothelioma

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